Detroit Lions at Buffalo Bills prediction

NFL Week 2, 2026 · Thu, Sep 17, 2026, 7:15 PM CT · Highmark Stadium. PLP IQ's straight-up, spread and total picks for this game, with confidence and PLAY / LEAN / PASS ratings, were locked at kickoff and graded against the final score.

Saved PLP IQ prediction

Predicted score DET 26 - BUF 31 · saved Thu, Sep 17, 2026, 10:35 AM CT · Final DET 31 - BUF 41

Straight upBUF · 60% · LEAN · WIN
Against the spreadDET +5.5 (line BUF -5.5) · 53% · PASS · LOSS
TotalOver 54.5 (line 54.5) · 55% · PASS · WIN

Loading live matchup data…